肝腫瘍の病理学研究

主な担当メンバー：山内直子、田中麻理子

私達の研究室では、肝細胞癌の新しい診断マーカーの探索や悪性度に関わる因子の研究を進めています。


＜参考文献＞

  1. The glypican 3 oncofetal protein is a promising diagnostic marker for hepatocellular carcinoma.
    Yamauchi N1, Watanabe A, Hishinuma M, Ohashi K, Midorikawa Y, Morishita Y, Niki T, Shibahara J, Mori M, Makuuchi M, Hippo Y, Kodama T, Iwanari H, Aburatani H, Fukayama M. Mod Pathol. 2005 Dec;18(12):1591-8.
  2. Concurrent activation of acetylation and tri-methylation of H3K27 in a subset of hepatocellular carcinoma with aggressive behavior.
    Hayashi A, Yamauchi N, Shibahara J, Kimura H, Morikawa T, Ishikawa S, Nagae G, Nishi A, Sakamoto Y, Kokudo N, Aburatani H, Fukayama M. PLoS One. 2014 Mar 10;9(3):e91330.
  3. Altered expression of AT-rich interactive domain 1A in hepatocellular carcinoma.
    Abe H, Hayashi A, Kunita A, Sakamoto Y, Hasegawa K, Shibahara J, Kokudo N, Fukayama M. Int J Clin Exp Pathol. 2015;8(3):2763-70.