2021年度業績

英文論文
  1. Abe H, Kunita A, Otake Y, Kanda T, Kaneda A, Ushiku T, Fukayama M. Virus-host interactions in carcinogenesis of Epstein-Barr virus-associated gastric carcinoma: Potential roles of lost ARID1A expression in its early stage. PLoS One. 2021;16(9):e0256440. doi: 10.1371/journal.pone.0256440. PMID:34469459.
  2. Abe H, Yasunaga Y, Yamazawa S, Nakai Y, Gonoi W, Nishioka Y, Murono K, Sasaki K, Arita J, Kawai K, Nozawa H, Hasegawa K, Ishihara S, Ushiku T. Histological growth patterns of colorectal cancer liver metastases: a strong prognostic marker associated with invasive patterns of the primary tumor and p53 alteration. Hum Pathol. 2022;123:74-83. doi:10.1016/j.humpath.2022.02.015. PMID:35247436.
  3. Akiyama Y, Miyakawa J, O’Donnell MA, Kreder KJ, Luo Y, Maeda D, Ushiku T, Kume H, Homma Y. Overexpression of HIF1α in Hunner Lesions of Interstitial Cystitis: Pathophysiological Implications. J Urol. 2022;207(3):635-646.　doi:10.1097/JU.0000000000002278. PMID:34694138.
  4. Ando T, Kage H, Shinozaki-Ushiku A, Tatsuno K, Tsutsumi S, Nagayama K, Nakajima J, Kohsaka S, Miyagawa K, Aburatani H, Mano H, Nagase T. Composite Clonal Analysis Reveals Transition of NSCLC Subtypes Through Accumulation of Gene Mutations: A Case Report. JTO Clin Res Rep. 2022;3(2):100277.　doi:10.1016/j.jtocrr.2022.100277.　PMID:35199052.
  5. Arai J, Aoki T, Sato M, Niikura R, Suzuki N, Ishibashi R, Tsuji Y, Yamada A, Hirata Y, Ushiku T, Hayakawa Y, Fujishiro M. Machine learning-based personalised prediction of gastric cancer incidence using the endoscopic and histological findings at the initial endoscopy. Gastrointest Endosc. 2022;S0016-5107(22)00001-3. doi:10.1016/j.gie.2021.12.033. PMID:34998795.
  6. Fujii Y, Sato Y, Suzuki H, Kakiuchi N, Yoshizato T, Lenis AT, Maekawa S, Yokoyama A, Takeuchi Y, Inoue Y, Ochi Y, Shiozawa Y, Aoki K, Yoshida K, Kataoka K, Nakagawa MM, Nannya Y, Makishima H, Miyakawa J, Kawai T, Morikawa T, Shiraishi Y, Chiba K, Tanaka H, Nagae G, Sanada M, Sugihara E, Sato TA, Nakagawa T, Fukayama M, Ushiku T, Aburatani H, Miyano S, Coleman JA, Homma Y, Solit DB, Kume H, Ogawa S. Molecular classification and diagnostics of upper urinary tract urothelial carcinoma. Cancer Cell. 2021;39(6):793-809.e8. doi:10.1016/j.ccell.2021.05.008. PMID:34129823.
  7. Hamada T, Oyama H, Nakai Y, Tada M, Koh H, Tateishi K, Arita J, Hakuta R, Ijichi H, Ishigaki K, Kawaguchi Y, Kogure H, Mizuno S, Morikawa T, Saito K, Saito T, Sato T, Takagi K, Takahara N, Takahashi R, Tanaka A, Tanaka M, Ushiku T, Hasegawa K, Koike K. ABO Blood Group and Risk of Pancreatic Carcinogenesis in Intraductal Papillary Mucinous Neoplasms. Cancer Epidemiol Biomarkers Prev. 2021;5:1020-1028. doi:10.1158/1055-9965.EPI-20-1581. PMID:33653811.
  8. Harada Y, Kazama S, Morikawa T, Sonoda H, Ishi H, Emoto S, Murono K, Kaneko M, Sasaki K, Shuno Y, Nishikawa T, Tanaka T, Kawai K, Hata K, Nozawa H, Ushiku T, Tahara H, Ishihara S. Clinical significance of CD8+ and FoxP3+ tumor-infiltrating lymphocytes and MFG-E8 expression in lower rectal cancer with preoperative chemoradiotherapy. Mol Clin Oncol. 2021;14(5):87. doi:10.3892/mco.2021.2249. PMID:33767856.
  9. Hinata M, Ushiku T. Detecting immunotherapy-sensitive subtype in gastric cancer using histologic image-based deep learning. Scientific Reports. 2021;11(1):22636. doi:10.1038/s41598-021-02168-4. PMID:34811485.
  10. Hiroyoshi J, Ishizawa T, Abe H, Arita J, Akamatsu N, Kaneko J, Ushiku T, Hasegawa K.　Identification of Glisson’s Capsule Invasion During Hepatectomy for Colorectal Liver Metastasis by Contrast-Enhanced Ultrasonography Using Perflubutane. World J Surg. 2021;45:1168-1177. doi:10.1007/s00268-020-05883-7. PMID33392704.
  11. Ideyama M, Abe H, Mori K, Yamagata Y, Seto Y, Ushiku T. Acquired mini-stomach development in the esophagus after caustic injury. Pathol Int. 2021;71(11):792-794. doi:10.1111/pin.13162. PMID:34499789.
  12. Imai S, Ooki T, Murata-Kamiya N, Komura D, Tahmina K, Wu W, Takahashi-Kanemitsu A, Knight CT, Kunita A, Suzuki N, Del Valle AA, Tsuboi M, Hata M, Hayakawa Y, Ohnishi N, Ueda K, Fukayama M, Ushiku T, Ishikawa S, Hatakeyama M. Helicobacter pylori CagA elicits BRCAness to induce genome instability that may underlie bacterial gastric carcinogenesis. Cell Host Microbe. 2021;29(6):941-958.e10. doi:10.1016/j.chom.2021.04.006. PMID:33989515.
  13. Ishida M, Gonoi W, Abe H, Shirota G, Fujimoto K, Okimoto N, Ushiku T, Abe O. Longitudinal comparison of ascites attenuation between antemortem and postmortem computed tomography. Forensic Sci Int. 2021;321:110727. doi:10.1016/j.forsciint.2021.110727. PMID:33636473.
  14. Ishigami D, Miyawaki S, Nakatomi H, Takayanagi S, Teranishi Y, Ohara K, Hongo H, Dofuku S, Kin T, Abe H, Mitsui J, Komura D, Katoh H, Ishikawa S, Saito N. Brainstem intraparenchymal schwannoma with genetic analysis: a case report and literature review. BMC Med Genomics. 2021;14(1):205. doi:10.1186/s12920-021-01049-z. PMID:34407809.
  15. Iwasaki A, Shinozaki-Ushiku A, Kunita A, Yamazawa S, Sato Y, Yamashita H, Fukayama M, Seto Y, Ushiku T. Human Leukocyte Antigen Class I Deficiency in Gastric Carcinoma: An Adaptive Immune Evasion Strategy Most Common in Microsatellite Instable Tumors. Am J Surg Pathol. 2021;45(9):1213-1220. doi:10.1097/PAS.0000000000001779. PMID:34310369.
  16. Kaneko M, Nozawa H, Rokutan H, Murono K, Ushiku T, Ishihara S. Ectopic decidua of the appendix: a case report. Surg Case Rep. 2021;7(1):117. doi:10.1186/s40792-021-01204-9. PMID:33973073.
  17. Kashima J, Hishima T, Okuma Y, Horio H, Ogawa M, Hayashi Y, Horiguchi SI, Motoi T, Ushiku T, Fukayama M. CD70 in Thymic Squamous Cell Carcinoma: Potential Diagnostic Markers and Immunotherapeutic Targets. Front Oncol. 2022;11:808396. doi:10.3389/fonc.2021.808396. PMID:35145909.
  18. Kato S, Kubota Y, Sekiguchi M, Watanabe K, Shinozaki-Ushiku A, Takita J, Hiwatari M. KMT2A-rearranged diffuse large B-cell lymphoma in a child: a case report and molecular characterization. Pediatr Hematol Oncol. 2021;38(3):281-289. doi:10.1080/08880018.2020.1838013. PMID:33150819.
  19. Kobayashi H, Makise N, Ito N, Koga M, Zhang L, Ishibashi Y, Ikegami M, Shinoda Y, Akiyama T, Ushiku T, Tanaka S. Surgical margin for phosphaturic mesenchymal tumors in soft tissues: An analysis of the radiological histopathological correlation. J Orthop Sci.2021;26(5):870-877. doi:10.1016/j.jos.2020.07.006. PMID:32798110.
  20. Kobayashi H, Makise N, Shinozaki-Ushiku A, Ishibashi Y, Ikegami M, Kohsaka S, Ushiku T, Oda K, Miyagawa K, Aburatani H, Mano H, Tanaka S. Scapular Angiomatoid Fibrous Histiocytoma with EWSR1-CREB1 Fusion in an Adult Patient. Case Rep Orthop. 2021;2021:9434222. doi:10.1155/2021/9434222. PMID:34631187.
  21. Komine R, Kojima M, Ishi G, Kudo M, Sugimoto M, Kobayashi S, Takahashi S, Konishi M, Kobayashi T, Akimoto T, Murakami A, Sasaki M, Tanaka M, Matsuzaki A, Ohike N, Uchida K, Sugiyama T, Hirabayashi K, Tajiri T, Ishida K, Kai K, Omori Y, Notohara K, Yamaguchi H, Matsuda Y, Naito Y, Fukumura Y, Hamada Y, Mihara Y, Masugi Y, Gotohda N, Harada K, Fukushima N, Furukawa T. Recognition and pathological features of periampullary region adenocarcinoma with an indeterminable origin. Cancer Med. 2021;10(11):3499. doi:10.1002/cam4.3809. PMID:34008914.
  22. Komura D, Kawabe A, Fukuta K, Sano K, Umezaki T, Koda H, Suzuki R, Tominaga K, Ochi M, Konishi H, Masakado F, Saito N, Sato Y, Onoyama T, Nishida S, Furuya G, Katoh H, Yamashita H, Kakimi K, Seto Y, Ushiku T, Fukayama M, Ishikawa S. Universal encoding of pan-cancer histology by deep texture representations. Cell Rep. 2022;38(9):110424. doi:10.1016/j.celrep.2022.110424. PMID:35235802.
  23. Koya J, Saito Y, Kameda T, Kogure Y, Yuasa M, Nagasaki J, McClure M.B., Shingak Si, Tabata M, Tahira Y, Akizuki K, Kamiunten A, Sekine M, Shide K, Kubuki Y, Hidaka T, Kitanaka A, Nakano N, Utsunomiya A, Togashi Y, Ogawa S, Shimoda K, Kataoka K. Single-Cell Analysis of the Multicellular Ecosystem in Viral Carcinogenesis by HTLV-1. Blood Cancer Discov. 2021;2(5):450-467. doi:10.1158/2643-3230.BCD-21-0044. PMID:34661162.
  24. Kudo N, Kudoh S, Matsuo A, Motooka Y, Ito T. ZMYM3 may promote cell proliferation in small cell lung carcinoma. Acta Histochem Cytochem. 2021;54(5):143–153. doi:10.1267/ahc.21-00012. PMID:34764523.
  25. Kuroe T, Watanabe R, Kojima M, Morisue R, Sugano M, Kuwata T, Masuda H, Kusuhara S, Matsubara N, Oda S, Ushiku T, Ishii G. Evaluation of the morphological features and unfavorable prognostic impact of dirty necrosis in renal cell carcinoma. J Cancer Res Clin Oncol. 2021;147(4):1089-1100. doi: 10.1007/s00432-020-03505-2. PMID: 33475860.
  26. Li W, Okabe A, Usui G, Fukuyo M, Matsusaka K, Rahmutulla B, Mano Y, Hoshii T, Funata S, Hiura N, Fukayama M, Tan P, Ushiku T, Kaneda A. Activation of EHF via STAT3 phosphorylation by LMP2A in Epstein-Barr virus-positive gastric cancer. Cancer Sci. 2021;112(8):3349-3362. doi:10.1111/cas.14978. PMID:34014591.
  27. Makise N, Yoshida KI, Iijima T, Yoshida A, Ushiku T, Ishida T. Skeletal EWSR1-NFATC2 sarcoma previously diagnosed as Ewing-like adamantinoma: A case report and literature review emphasizing its unique radiological features. Pathol Int. 2021;71(9):614-620. doi:10.1111/pin.13135. PMID:34192825.
  28. Murakami D, Maki H, Matsuda K, Masamoto Y, Suzuki F, Amemiya S, Osawa K, Hinata M, Ikemura M, Ushiku T, Kurokawa M. Cerebral toxoplasmosis complicating lymphoplasmacytic lymphoma in partial remission. J Infect Chemother. 2022;28(2):279-282. doi:10.1016/j.jiac.2021.09.005. PMID:34580008.
  29. Nagano M, Kohsaka S, Hayashi T, Ueno T, Kojima S, Shinozaki-Ushiku A, Morita S, Tsuda M, Tanaka S, Shinohara T, Omori Y, Sugaya F, Kato H, Narita Y, Nakajima J, Suzuki K, Takamochi K, Mano H. Comprehensive molecular profiling of pulmonary pleomorphic carcinoma. NPJ Precis Oncol. 2021;5(1):57. doi:10.1038/s41698-021-00201-3. PMID:34158601.
  30. Nakase M, Asami M, Yahagi K, Sato Y, Nakayama A, Ninomiya K, Tanaka T, Horiuchi Y, Yuzawa H, Komiyama K, Tanaka J, Aoki J, Virmani R, Mori M, Tanabe K. Autopsy findings of left atrial appendage closure device. Cardiovasc Pathol. 2022;56:107384 doi:10.1016/j.carpath.2021.107384. PMID:34534669.
  31. Nakazaki K, Yoshida M, Masamoto Y, Shinozaki-Ushiku A, Ikemura M, Hisamoto T, Yasunaga M, Sato S, Kurokawa M. Discordant lymphomas of classic Hodgkin lymphoma and peripheral T-cell lymphoma following dupilumab treatment for atopic dermatitis. Int J Hematol. 2022;Epub ahead of print. doi:10.1007/s12185-022-03330-y. PMID:35355217.
  32. Ogasawara N, Kikuchi D, Inoshita N, Nakayama A, Kohno K, Ochiai Y, Hayasaka J, Suzuki Y, Dan N, Okamura T, Mitsunaga Y, Tanaka M, Nomura K, Odagiri H, Yamashita S, Matsui A, Hoteya S, and Iizuka T. Metachronous carcinogenesis of superficial esophagus squamous cell carcinoma after endoscopic submucosal dissection: incidence and risk stratification during long-term observation. Esophagus. 2021;18(4):806-816. doi:10.1007/s10388-021-00848-8. PMID:33974189.
  33. Ohki D, Tsuji Y, Yamazawa S, Ushiku T, Tateishi K. Gastrointestinal: Esophageal adenocarcinoma arising from circumferential ectopic gastric mucosa: A case report. J Gastroenterol Hepatol. 2022;37(1):47. doi:10.1111/jgh.15602. PMID:34279045.
  34. Oki R, Hirakawa Y, Oda Y, Nakamura M, Honda K, Abe H, Domoto Y, Miyashita N, Nagase T, Nangaku M. Renal-limited ANCA-associated vasculitis during erlotinib treatment for lung carcinoma. CEN Case Rep. 2022;11(1):67-72. doi:10.1007/s13730-021-00632-8. PMID:34309804.
  35. Okimoto N, Ishida M, Abe H, Ikemura M, Fujimoto K, Kanemaru N, Ushiku T, Abe O, Gonoi W. Delayed cerebral enhancement on post-mortem computed tomography due to residual contrast medium administered shortly before death. Radiol Case Rep. 2021;16(8):2056-2060. doi:10.1016/j.radcr.2021.04.065. PMID:34158893.
  36. Okubo Y, Sato S, Osaka K, Yamamoto Y, Suzuki T, Ida A, Yoshioka E, Suzuki M, Washimi K, Yokose T, Kishida T, Miyagi Y. Clinicopathological analysis of the ISUP Grade group and other parameters in prostate cancer: Elucidation of mutual impact of the various parameters. Front Oncol. 2021;11:695251. doi:10.3389/fonc.2021.695251. PMID:34395260.
  37. Ozaki K, Kawai K, Nozawa H, Sasaki K, Murono K, Emoto S, Abe H, Ushiku T, Ishihara S. Impact of the viability assessment of lateral lymph node metastasis in rectal cancer after neoadjuvant chemoradiotherapy. Int J Colorectal Dis. 2022;37(2):467-473. doi:10.1007/s00384-021-04085-4. PMID:35064299.
  38. Saito H, Tenjin Y, Yamada T, Kudoh S, Kudo N, Sanada M, Sato Y, Matsuo A, Orita Y, Ito T. The role of YAP1 in small cell lung cancer. Hum Cell. 2022;35(2):628–638. doi:10.1007/s13577-022-00669-6. PMID:35072899.
  39. Sakamoto A, Nozawa H, Sonoda H, Hinata M, Ishii H, Emoto S, Anzai H, Yokoyama Y, Murono K, Sasaki K, Kawai K, Ushiku T, Ishihara S. Rectal neuroendocrine tumor with extracapsular lymph node metastasis: a case report. Clin J Gastroenterol. 2021;14(5):1426-1430. doi:10.1007/s12328-021-01447-x. PMID:34028785.
  40. Sasaki K, Honda A, Shinozaki-Ushiku A, Fujioka Y, Maki H, Toyama K, Ushiku T, Kurokawa M. A case of transplantation-associated thrombotic microangiopathy with autopsy-proven fatal myocardial ischemia after allogeneic hematopoietic stem cell transplantation. Ann Hematol. 2021;100(6):1621-1622. doi:10.1007/s00277-020-04027-0. PMID:32372148.
  41. Sato A, Tanabe M, Tsuboi Y, Niwa T, Shinozaki-Ushiku A, Seto Y, Murakami Y. Circulating Tumor DNA Harboring the BRAFV600E Mutation May Predict Poor Outcomes of Primary Papillary Thyroid Cancer Patients. Thyroid. 2021;31(12):1822-1828. doi:10.1089/thy.2021.0267. PMID:34541884.
  42. Sato S, Chang SH, Kasai T, Maenohara Y, Yamazawa S, Tanaka S, Matsumoto T. Juvenile Dysplasia Epiphysealis Hemimelica with Multiple Ankle Free Body. Case Reports in Orthopedics. 2021;2021:5579684. doi:10.1155/2021/5579684. PMID:33898071.
  43. Shi C, Badgwell BD, Grabsch HI, Gibson MK, Hong SM, Kumarasinghe P, Lam AK, Lauwers G, O’Donovan M, van der Post RS, Tang L, Ushiku T, Vieth M, Selinger CI, Webster F, Nagtegaal ID. Data Set for Reporting Carcinoma of the Stomach in Gastrectomy. Arch Pathol Lab Med. 2021;Epub ahead of print. doi:10.5858/arpa.2021-0225-OA. PMID:34919649.
  44. Shibayama T, Makise N, Motoi T, Mori T, Hiraoka N, Yonemori K, Watanabe SI, Esaki M, Morizane C, Okuma T, Kawai A, Ushiku T, Yatabe Y, Yoshida A. Clinicopathologic Characterization of Epithelioid Hemangioendothelioma in a Series of 62 Cases: A Proposal of Risk Stratification and Identification of a Synaptophysin-positive Aggressive Subset. Am J Surg Pathol. 2021;45(5):616-626. doi:10.1097/PAS.0000000000001660. PMID:33729740.
  45. Sone K, Inoue F, Taguchi A, Hinata M, Ikemura M, Miyamoto Y, Michihiro T, Ohno T, Iriyama T, Mori-Uchino M, Tsuruga T, Mishima M, Osuga Y. A case of difficult-to-diagnose non-invasive papillary squamous cell carcinoma of the uterine cervix infected with human papilloma virus 6: A diagnostic pitfall. Clin Case Rep. 2021;9(10):e04905. doi:10.1002/ccr3.4905. PMID:34631088.
  46. Sone K, Kukita A, Masui Y, Yamada D, Shinozaki-Ushiku A, Kawata A, Taguchi A, Miyamoto Y, Tanikawa M, Iriyama T, Mori-Uchino M, Tsuruga T, Osuga Y. Recurrent malignant melanoma of the uterine cervix treated with anti-PD-1 antibodies and anti-CTLA-4 antibodies: A case report. Mol Clin Oncol. 2022;16(3):63. doi:10.3892/mco.2022.2496. PMID:35154703.
  47. Sueyoshi K, Komura D, Katoh H, Yamamoto A, Onoyama T, Chijiwa T, Isagawa T, Tanaka M, Suemizu H, Nakamura M, Miyagi Y, Aburatani H, Ishikawa S. Multi-tumor analysis of cancer-stroma interactomes of patient-derived xenografts unveils the unique homeostatic process in renal cell carcinomas. iScience. 2021;24(11):103322. doi:10.1016/j.isci.2021.103322. PMID:35079698.
  48. Suzuki S, Kurokawa R, Tsuruga T, Mori-Uchino M, Nishida H, Kato T, Abe H, Ushiku T, Amemiya S, Katayama A, Abe O. CT, MRI, and FDG-PET imaging findings of low-grade extrauterine endometrial stromal sarcoma arising from the mesentery:A case report. Radiol Case Rep. 2021;16(9):2774-2779. doi:10.1016/j.radcr.2021.06.063. PMID:34367393.
  49. Tachikawa Y, Nozawa H, Hata K, Abe H, Ushiku T, Ishihara S. Metachronous ileal cancer after surgery for ascending colon cancer in a patient with Lynch syndrome: A case report. Int J Surg Case Rep. 2021;81:105714. doi:10.1016/j.ijscr.2021.105714. PMID:33684646.
  50. Taguchi A, Rokutan H, Oda K, Tanikawa M, Tanimoto S, Sone K, Mori M, Tsuruga T, Kohsaka S, Tatsuno K, Shinozaki-Ushiku A, Miyagawa K, Mano H, Aburatani H, Ushiku T, Osuga Y. Genetic diagnosis of pseudomyxoma peritonei originating from mucinous borderline tumor inside an ovarian teratoma. BMC Med Genomics. 2022;15(1):51. doi:10.1186/s12920-022-01188-x. PMID:35255903.
  51. Taguchi J, Shibata H, Kabata M, Kato M, Fukuda K, Tanaka A, Ohta S, Ukai T, Mitsunaga K, Yamada Y, Nagaoka SI, Yamazawa S, Ohnishi K, Woltjen K, Ushiku T, Ozawa M, Saitou M, Shinkai Y, Yamamoto T, Yamada Y. DMRT1-mediated reprogramming drives development of cancer resembling human germ cell tumors with features of totipotency. Nat Commun. 2021;12(1):5041. doi:10.1038/s41467-021-25249-4. PMID:34413299.
  52. Takahashi R, Ishizawa T, Sato M, Inagaki Y, Tanaka M, Kuriki Y, Kamiya M, Ushiku T, Urano Y, Hasegawa K. Fluorescence Imaging Using Enzyme-Activatable Probes for Real-Time Identification of Pancreatic Cancer. Front Oncol. 2021;11:714527. doi:10.3389/fonc.2021.714527. PMID:34490111.
  53. Takamiya A, Ishibashi Y, Makise N, Hirata M, Ushiku T, Tanaka S, Kobayashi H. Imaging characteristics of NTRK-rearranged spindle cell neoplasm of the soft tissue: A case report. J Orthop Sci. 2022;S0949-2658(21)00367-5. doi:10.1016/j.jos.2021.11.002. PMID:35033373.
  54. Takano H, Yasunaga M, Yamazaki I, Nishikawa M, Masamoto Y, Shinozaki-Ushiku A, Kawakami M, Yatomi Y, Kurokawa M. Degenerated mitochondria in leukemic blast appeared as granules on May-Grunwald-Giemsa staining. Ann Hematol. 2022;101(5):1135-1136. doi:10.1007/s00277-021-04684-9. PMID:34664090.
  55. Takumida H, Izumi S, Sakamoto K, Hashimoto M, Ishii S, Suzuki M, Takasaki J, Tanaka M, Igari T, Hojo M. Sustained coronavirus disease 2019-related organizing pneumonia successfully treated with corticosteroid. Respir Investig. 2021;59(3):377-381. doi:10.1016/j.resinv.2020.12.005. PMID:33547007.
  56. Tanaka R, Kaburaki T, Taoka K, Karakawa A, Tsuji H, Nishikawa M, Yatomi Y, Shinozaki-Ushiku A, Ushiku T, Araki F. More Accurate Diagnosis of Vitreoretinal Lymphoma Using a Combination of Diagnostic Test Results: A Prospective Observational Study. Ocul Immunol Inflamm. 2021;Epub ahead of print:1-7. doi:10.1080/09273948.2021.1873394. PMID:33793360.
  57. Tawara N, Nakane S, Kudo N, Kosaka T, Takamatsu K, Wada K, Kobayashi A, Yamashita S, Funagura N, Inoue T, Ando Y. Binasal hemianopia caused by bilateral optic perineuritis due to sarcoidosis. eNeurologicalSci. 2021;24:100354. doi:10.1016/j.ensci.2021.100354. PMID:34466671.
  58. Torimitsu S, Abe H, Makino Y, Yamaguchi R, Motomura A, Hoshioka Y, Iwase H. Streptococcal toxic shock syndrome with fatal outcome: Report on four forensic autopsy cases. Leg Med (Tokyo). 2021;50:101851. doi:10.1016/j.legalmed.2021.101851. PMID:33578046.
  59. Torimoto K, Okuno K, Kuroda R, Shanas N, Cicalese SM, Eguchi K, Elliott KJ, Kawai T, Corbett CB, Peluzzo AM, St Paul AK, Autieri MV, Scalia R, Rizzo V, Hashimoto T, Eguchi S. Glucose consumption of vascular cell types in culture: toward optimization of experimental conditions. Am J Physiol Cell Physiol. 2022;322(1):C73-C85. doi:10.1152/ajpcell.00257.2021. PMID:34817269.
  60. Tsuda Y, Kobayashi H, Makise N, Zhang L, Shinoda Y, Ushiku T, Tanaka S. Hemangioma of the Rib Mimicking Chondrosarcoma: A Report of Two Cases and Literature Review. Case Rep Orthop. 2021;2021:9996380. doi:10.1155/2021/9996380. PMID:34621554.
  61. Tsuzuki S, Komai T, Terada K, Tsuchida Y, Tanaka M, Tateishi Y, Shinozaki-Ushiku A, Shoda H, Fujio K. Nailfold capillaroscopic abnormalities in angioedema with eosinophilia.　Allergol Int. 2021;70(4):501-503. doi:10.1016/j.alit.2021.04.007. PMID:34049796.
  62. Yachida S, Totoki Y, Noë M, Nakatani Y, Horie M, Kawasaki K, Nakamura H, Saito-Adachi M, Suzuki M, Takai E, Hama N, Higuchi R, Hirono S, Shiba S, Kato M, Furukawa E, Arai Y, Rokutan H, Hashimoto T, Mitsunaga S, Kanda M, Tanaka H, Takata S, Shimomura A, Oshima M, Hackeng WM, Okumura T, Okano K, Yamamoto M, Yamaue H, Morizane C, Arihiro K, Furukawa T, Sato T, Kiyono T, Brosens LAA, Wood LD, Hruban RH, Shibata T. Comprehensive Genomic Profiling of Neuroendocrine Carcinomas of the Gastrointestinal System. Cancer Discov. 2022;12(3);692-711. doi:10.1158/2159-8290.CD-21-0669. PMID:34880079.
  63. Yamada S, Kanda H, Abe H, Domoto YS, Yoshida R, Harada H, Kubo K, Ushiku T, Fujio K. Predominant mesangial IgM, C3, and λ light chain depositions and interstitial nephritis in a patient with overlap syndrome and positivity for anti-mitochondrial M2 antibody: a case report. Mod Rheumatol Case Rep. 2022;6(1):124-127. doi:10.1093/mrcr/rxab017. PMID:34505626.
  64. Yamamoto A, Tateishi Y, Aikou S, Seto Y, Ushiku T. The first case of gastric leiomyosarcoma developed through malignant transformation of leiomyoma. Pathol Int. 2021;71(12):837-843. doi:10.1111/pin.13165. PMID:34520615.
  65. Yamashita M, Ikeda M, Kato I, Ohama Y, Ando M, Ikemura M, Jubishi D, Kanno Y, Okamoto K, Umeyama T, Nakamura S, Miyazaki Y, Okugawa S, Moriya K. Protothecosis in the mucosa of the pharynx mimicking pharyngeal cancer in an immunocompetent individual: a case report. Ann Clin Microbiol Antimicrob. 2022;21(1):5. doi:10.1186/s12941-022-00495-6. PMID:35164794.
  66. Yamazawa S, Ushiku T. Carcinosarcoma of the stomach: four cases that expand the morphologic spectrum of gastric cancer with a primitive phenotype. Virchows Arch. 2022;480(5):1051-1062. doi:10.1007/s00428-022-03307-6. PMID:35243539.
  67. Yoshioka K, Kurokawa R, Amemiya S, Koyamaa H, Matsuda K, Honda A, Kurokawa M, Shinozaki-Ushiku A, Abe O. Rapidly progressing blastic plasmacytoid dendritic cell neoplasm causing diffuse skin thickening: A case report with sequential computed tomography examinations. Radiol Case Rep. 2021;16(10):2929-2933. doi:10.1016/j.radcr.2021.07.010. PMID:34401028.
  68. Zhang CD, Takeshima H, Sekine S, Yamashita S, Liu YY, Hattori N, Abe H, Yamashita H, Fukuda M, Imamura Y, Ushiku T, Katai H, Makino H, Watanabe M, Seto Y, Ushijima T. Prediction of tissue origin of adenocarcinomas in the esophagogastric junction by DNA methylation. Gastric Cancer. 2022;25(2):336-345. doi:10.1007/s10120-021-01252-y. PMID:34557982.
和文論文
  1. 日向宗利, 阿部浩幸, 黒瀬優介, 原田達也, 深山正久, 牛久哲男．消化管疾患におけるAI病理診断．胃と腸 2021;56(4):401-410.
  2. 平田雄一郎, 飯田俊, 新城雄士, 斉藤久子, 永澤明佳, 阿部浩幸, 池村雅子, 鈴木忠樹, 牛久哲男, 秋冨慎司. COVID-19患者遺体の病理解剖実態調査 (2020年4月から2021年1月) 診断病理 2021;38(4): 374-382.
英文総説・著書
  1. Abe H, Ushiku T. Pathological diversity of gastric cancer from the viewpoint of background condition. Digestion. 2022;103:45-53. doi:10.1159/000519337. PMID:34628409.
  2. Shi C, Badgwell B, Gibson MK, Grabsch HI, Hong S, Kumarasinghe P, Lam A, Lauwers G, O’Donovan M, Tang L, Ushiku T, van der Post C, Vieth M, Nagtegaal ID (2021). Carcinoma of the Stomach Histopathology Reporting Guide, 2nd edition. International Collaboration on Cancer Reporting; Sydney, Australia.
  3. Shi C, Bourke M, Hong S, Kumarasinghe P, Lam A, Lauwers G, O’Donovan M, Ushiku T, van der Post C, Vieth M, Nagtegaal ID (2021). Endoscopic Resection of the Stomach Histopathology Reporting Guide, 2nd edition. International Collaboration on Cancer Reporting; Sydney, Australia.
和文総説・著書
  1. 阿部浩幸, 牛久哲男．虫垂上皮性腫瘍　腺腫. 腫瘍病理鑑別診断アトラス 十二指腸・小腸・虫垂腫瘍 2021:65-68.
  2. 阿部浩幸, 黒瀬優介, 原田達也, 牛久哲男, 深山正久．胃生検組織診断での 病理と臨床 2021;39(8):789-792.
  3. 阿部浩幸, 牛久哲男. 抗HER2薬対象患者の選択方法　乳癌・胃癌HER2病理診断ガイドライン 第2版 2021:78-83.
  4. 阿部浩幸．AI技術と画像診断②―病理―. 最新医療情報誌アニムス 2022;109:27-32.
  5. 阿部浩幸．EB ウイルス関連胃癌の病理学的特徴. 日本臨牀 2022;80(増刊号3):134-138.
  6. 阿部浩幸, 日向宗利, 国田朱子, 牛久綾, 牛久哲男．Epstein-Barrウイルス関連胃癌の新展開―Epstein-Barrウイルス関連胃癌の病理学. 胃と腸 2021;56(10):1339-1345.
  7. 阿部浩幸．未分化癌．腫瘍病理鑑別診断アトラス 食道癌 第2版 2021:87-89.
  8. 池村雅子．中枢神経系の検索方法. 診断病理 2021;38(4):341-349.
  9. 池村雅子, 牛久哲男．より診断精度を上げるためのトピック 病理診断. Medical Practice 2021;38(11):1723-1726.
  10. 牛久綾．単形成上皮向性腸管T細胞リンパ腫（MEITL)と腸症関連Ｔ細胞リンパ腫(EATL). 腫瘍病理鑑別診断アトラス 十二指腸・小腸・虫垂腫瘍 2021:128-133.
  11. 牛久哲男．十二指腸上皮性腫瘍 腺癌. 腫瘍病理鑑別診断アトラス 十二指腸・小腸・虫垂腫瘍 2021:42-49.
  12. 牛久哲男．食道の解剖学・組織学．腫瘍病理鑑別診断アトラス 食道癌 第2版　2021:26-31.
  13. 牛久哲男（編集・執筆）．医原性病変の病理 – 診断医が知っておきたい組織所見 -消化管 病理と臨床 2021;39(5): 430-437,
  14. 牛久哲男．Ring mitosis 病理と臨床 2021; 39(6): 606-609.
  15. 十二指腸癌診療ガイドライン作成委員会（病理委員：牛久哲男）. 十二指腸癌診療ガイドライン2021年版
  16. 牛久哲男．非乳頭部十二指腸腫瘍の病理 日本消化器病学会雑誌 2022;119(2):112-117.
  17. 牛久哲男．良悪性の鑑別が問題となる胃病変の病理学的特徴 消化器内科 2021;3(10):72-77.
  18. 牛久哲男（分担編集・執筆）十二指腸内視鏡図譜（中国語版）2021年11月（鳳凰医学）.
  19. 浦辺雅之、牛久哲男 食道胃接合部癌の生物学的特性－病理の立場から－ 消化器内科 2021;3(5):39-44.
  20. 岸野祐也, 三角健人, 宮﨑秀幹, 猪狩亨, 牛久哲男．COVID-19の他臓器病変. 病理と臨床2021;39(12):1233-1237.
  21. 立石陽子, 牛久哲男．虫垂上皮性腫瘍 低異型度虫垂粘液性腫瘍. 腫瘍病理鑑別診断アトラス 十二指腸・小腸・虫垂腫瘍 2021:69-73.
  22. 田中麻理子, 牛久哲男．コンパニオン診断．腫瘍病理鑑別診断アトラス 十二指腸・小腸・虫垂腫瘍 2021:200-207.
  23. 六反啓文．腺腫と分化型癌の組織分類の新展開―腺腫と分化型癌の組織発生と分類―初期変異を軸に. 胃と腸 2021;56(10):1253-1259.
  24. 六反啓文, 立石陽子, 牛久哲男．食道炎の最新知見と病理診断. 病理と臨床2021;39(6):530-536.
国内学会発表

第110回日本病理学会総会 2021年4月22日～24日 東京

[ワークショップ]
  1. 牧瀬尚大, 牛久哲男．新たな未分化円形細胞肉腫（CIC、BCOR、EWSR1-NFATC2 肉腫）．
  2. 六反啓文, 国田朱子, 柴田龍弘, 牛久哲男．手つなぎ型胃癌とびまん型胃癌をつなぐゲノム異常．
[スイーツセミナー]
  1. 牛久哲男.　がんパネルの実践：見えるもの、見なくてはいけないもの「病理医はレポートを通して何が見える、何をみるべきか」
[口演]
  1. 阿部浩幸．日本病理学会JP-AID成果報告．
  2. 阿部浩幸, 中井雄大, 五ノ井渉, 西岡裕次郎, 有田淳一, 長谷川潔, 佐々木和人, 石原聡一郎, 牛久哲男．大腸癌肝転移巣におけるhistological growth patternは原発巣浸潤先進部の形態と相関する．
  3. 岩﨑晶子, 阿部浩幸, 牛久哲男．SMARCA2とSMARCA4の同時欠失を示した胃未分化癌の2例．
  4. 加藤萌, 牛久綾, 国田朱子, 牛久哲男．マイクロサテライト不安定性小腸癌の臨床病理学的検討．
  5. 田中麻理子, 柴原純二, 加藤洋人, 石川俊平, 長谷川潔, 有田淳一, 柴田龍弘, 山岸誠, 深山正久, 牛久哲男．肝内胆管癌におけるKRASの意義．
  6. 日向宗利, 牛久哲男．深層学習を用いた免疫療法に感受性のある胃癌サブタイプの病理組織画像からの検出．
  7. 牧瀬尚大, 森泰昌, 元井亨, 柴原純二, 牛久哲男, 吉田朗彦．増殖性筋膜炎/筋炎はFOS遺伝子再構成を有する．
  8. 山下智, 阿部浩幸, 八木浩一, 山下裕玄, 瀬戸泰之, 牛久哲男．食道神経内分泌細胞癌においてはPD-1/PD-L1経路とHLA-Class Iが有望な治療標的である．
[示説]
  1. 井手山真, 髙澤豊, 藤井丈士, 中山敦仁, 宮本篤, 高井大哉．上葉優位型肺線維症の剖検例3例の臨床病理学的検討．
  2. 井手山真, 髙澤豊, 野村浩介, 布袋屋修．腺窩上皮型の形質を持つ胃型腫瘍のESD検体26例の臨床病理学的検討．
  3. 箱崎眞結, 仲泰史, 深山正久, 牛久哲男, 橋本唯史, 岩坪威．脳内でβアミロイドーシスを誘発する可溶な高分子量Aβオリゴマーの解析．
  4. 山澤 翔, 牛久 哲男．神経内分泌分化を示す胎児型胃癌の検討．
  5. 山本周, 立石陽子, 牛久哲男．平滑筋腫の悪性転化により生じた胃原発平滑筋肉腫の初の報告例．

第 90 回 日本病理学会関東支部学術集会 2021年5月5日 埼玉

  1. 近藤篤史, 六反啓文, 国田朱子, 牛久哲男．EBウイルス関連胃癌の進展過程で癌細胞からEBウイルスが消失した一例．[口演]

第62回日本臨床細胞学会総会 2021年6月4日～6日 千葉

  1. 牧瀬尚大, 牛久哲男．脊索腫とその亜型．[ワークショップ]

東大オープンキャンパス 2021年7月10～11日 オンライン

  1. 牛久哲男．病理医とがんをみる，知る，考える．[講義]

岡山大学病理学特別講義　2021年7月14日 岡山

  1. 牛久哲男．病理学特別講義 [講義]

Tokyo Gastrology Clinical Diagnosis Conference　2021年7月30日WEB開催

  1. 牛久哲男．どこを狙うかバイオプシー．[講演]

日本病理学会関東支部 夏の学校 2021　2021年8月28日WEB開催    

  1. 安永瑛一．大学での病理専門研修・大学院生活を終えて．[口演]

第711 回福井県胃腸疾患懇話会2021年8月28日

  1. 牛久哲男．特別講演「胃癌の病理診断の今－胎児型胃癌、EBV関連胃癌、手つなぎ型胃癌、胃底線型胃癌など」

第80回日本癌学会学術総会 2021年9月30日～10月2日 横浜

[口演]
  1. 近藤篤史, 六反啓文, 国田朱子, 牛久綾, 牛久哲男．EBV partially positive gastric cancer: evidence of hit-and-run carcinogenesis?
  2. 田中麻理子, 山岸誠, 国田朱子, 石川俊平, 加藤洋人, 長谷川潔, 有田淳一, 柴田龍弘, 牛久哲男．肝内胆管癌の臨床病理学的振る舞いにおけるKRASの意義．
  3. 六反啓文, 新井康仁, 国田朱子, 細田文恵, 柴田龍弘, 牛久哲男．手つなぎ型胃癌のゲノム異常・病理像・進展形式の解析．

The 12th Asia Pacific International Academy of Pathology Congress 2021年9月11－12日WEB開催

  1. 牛久哲男　シンポジウムGI “Carcinogenic role of Epstein-Barr virus in the development of gastric cancer”

第40回日本認知症学会学術集会 2021年11月26日～28日 東京

  1. 箱崎眞結, 牛久哲男, 橋本唯史, 岩坪威．アルツハイマー病患者脳由来Aβ seed分子のin vivoにおけるAβ蓄積誘発効果の検討．[示説]

日本医療情報学会　2021年11月18日～21日　名古屋

[口演]
  1. 阿部浩幸, 倉田盛人, 吉澤明彦, 深山正久, 北川昌伸．日本病理学会における病理画像データベース構築と利活用 ―臨床学会の立場から―．
  2. 阿部浩幸, 吉澤明彦, 深山正久, 北川昌伸．日本病理学会における病理診断支援AI開発　―Japan Pathology AI Diagnostics Project (JP-AID)―．

第91回日本病理学会関東支部学術集会 2021年10月9日WEB開催

  1. 井手山真, 阿部浩幸, 牛久哲男．食道の腐食性傷害部が長期経過後に胃のように変化した一例．[口演]

日本がん治療認定医機構教育セミナー 2021年10月22日～30日WEB開催

  1. 牛久綾．病理学（分子病理学を含む）．[セミナー]

日本病理学会 分子病理Up to date講習会 2022年1月22日WEB開催

  1. 牛久綾．がん遺伝子パネル検査のレポートとエキスパートパネル．[講習会]

第94回日本胃癌学会総会2022年3月2－4日 横浜

  1. 牛久哲男. プレナリーセッション 新しい胃癌取り扱い規約：新しい規約策定に向けた取り組み「分子サブタイプ分類を規約に組み込む必要性」
受賞

病理部　2021年度ベスト診療科賞
阿部浩幸．東京大学医学部Best Teacher’s Award.
小川優子　東大病院ベストスタッフ賞